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TRAIL-Based High Throughput Screening Reveals a Link between TRAIL-Mediated Apoptosis and Glutathione Reductase, a Key Component of Oxidative Stress Response.
Rozanov, Dmitri; Cheltsov, Anton; Sergienko, Eduard; Vasile, Stefan; Golubkov, Vladislav; Aleshin, Alexander E; Levin, Trevor; Traer, Elie; Hann, Byron; Freimuth, Julia; Alexeev, Nikita; Alekseyev, Max A; Budko, Sergey P; Bächinger, Hans Peter; Spellman, Paul.
Afiliação
  • Rozanov D; Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, Oregon, United States of America.
  • Cheltsov A; Q-MOL LLC, San Diego, CA, United States of America.
  • Sergienko E; Q-MOL LLC, San Diego, CA, United States of America.
  • Vasile S; The Conrad Prebys Center for Chemical Genomics, Sanford-Burnham Medical Research Institute, Orlando, Florida, United States of America.
  • Golubkov V; Inflammatory and Infectious Disease Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America.
  • Aleshin AE; Inflammatory and Infectious Disease Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America.
  • Levin T; Department of Biomedical Engineering, Oregon Health & Science University, Portland, Oregon, United States of America.
  • Traer E; Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon, United States of America.
  • Hann B; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, United States of America.
  • Freimuth J; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, United States of America.
  • Alexeev N; Computational Biology Institute, George Washington University, Ashburn, Virginia, United States of America; Department of Mathematics and Mechanics, Saint Petersburg State University, Saint Petersburg, Russia.
  • Alekseyev MA; Computational Biology Institute, George Washington University, Ashburn, Virginia, United States of America.
  • Budko SP; Research Department, Shriners Hospital for Children, Portland, Oregon, United States of America; Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon, United States of America.
  • Bächinger HP; Research Department, Shriners Hospital for Children, Portland, Oregon, United States of America; Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland, Oregon, United States of America.
  • Spellman P; Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, Oregon, United States of America.
PLoS One ; 10(6): e0129566, 2015.
Article em En | MEDLINE | ID: mdl-26075913
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apoptose / Estresse Oxidativo / Ligante Indutor de Apoptose Relacionado a TNF / Ensaios de Triagem em Larga Escala / Glutationa Redutase Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apoptose / Estresse Oxidativo / Ligante Indutor de Apoptose Relacionado a TNF / Ensaios de Triagem em Larga Escala / Glutationa Redutase Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos