BAFF-driven autoimmunity requires CD19 expression.

Fairfax, Kirsten A; Tsantikos, Evelyn; Figgett, William A; Vincent, Fabien B; Quah, Pin Shie; LePage, Mélanie; Hibbs, Margaret L; Mackay, Fabienne

Fairfax, Kirsten A; Tsantikos, Evelyn; Figgett, William A; Vincent, Fabien B; Quah, Pin Shie; LePage, Mélanie; Hibbs, Margaret L; Mackay, Fabienne.

Afiliação

Fairfax KA; Faculty of Medicine, Nursing and Health Sciences, Department of Immunology, Central Clinical School, Monash University, Commercial Rd, Melbourne 3004, Australia; The Walter and Eliza Hall Institute of Medical Research, Molecular Medicine Division, 1G Royal Parade, Melbourne 3052, Australia; The Depa
Tsantikos E; Faculty of Medicine, Nursing and Health Sciences, Department of Immunology, Central Clinical School, Monash University, Commercial Rd, Melbourne 3004, Australia.
Figgett WA; Faculty of Medicine, Nursing and Health Sciences, Department of Immunology, Central Clinical School, Monash University, Commercial Rd, Melbourne 3004, Australia.
Vincent FB; Faculty of Medicine, Nursing and Health Sciences, Department of Immunology, Central Clinical School, Monash University, Commercial Rd, Melbourne 3004, Australia.
Quah PS; Faculty of Medicine, Nursing and Health Sciences, Department of Immunology, Central Clinical School, Monash University, Commercial Rd, Melbourne 3004, Australia.
LePage M; Faculty of Medicine, Nursing and Health Sciences, Department of Immunology, Central Clinical School, Monash University, Commercial Rd, Melbourne 3004, Australia.
Hibbs ML; Faculty of Medicine, Nursing and Health Sciences, Department of Immunology, Central Clinical School, Monash University, Commercial Rd, Melbourne 3004, Australia.
Mackay F; Faculty of Medicine, Nursing and Health Sciences, Department of Immunology, Central Clinical School, Monash University, Commercial Rd, Melbourne 3004, Australia. Electronic address: Fabienne.Mackay@monash.edu.

J Autoimmun ; 62: 1-10, 2015 Aug.

Article em En | MEDLINE | ID: mdl-26103922

Assuntos

Antígenos CD19/genética; Autoimunidade/genética; Autoimunidade/imunologia; Fator Ativador de Células B/metabolismo; Regulação da Expressão Gênica; Animais; Autoanticorpos/imunologia; Subpopulações de Linfócitos B/imunologia; Subpopulações de Linfócitos B/metabolismo; Complemento C3/imunologia; Glomerulonefrite/genética; Glomerulonefrite/imunologia; Glomerulonefrite/metabolismo; Glomerulonefrite/patologia; Imunoglobulina G/imunologia; Imunoglobulina M/imunologia; Camundongos; Camundongos Knockout; Camundongos Transgênicos; Fenótipo; Transdução de Sinais; Receptores Toll-Like/metabolismo

Palavras-chave

Autoimmunity; B1b cells; BAFF; BAFF-transgenic; CD19; MZ B cells

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autoimunidade / Regulação da Expressão Gênica / Antígenos CD19 / Fator Ativador de Células B Limite: Animals Idioma: En Revista: J Autoimmun Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2015 Tipo de documento: Article

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