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BlastXtract2: Improving early exploration of (meta) genomes.
de Weerd, Heleen; van der Veen, Bernd E; Claesson, Marcus J.
Afiliação
  • de Weerd H; Microbiology and Systems Biology, TNO, Zeist, The Netherlands.
  • van der Veen BE; Genomics Core Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Claesson MJ; School of microbiology and alimentary pharmabiotic centre, university college cork, cork, Ireland.
Bioinformation ; 11(4): 173-5, 2015.
Article em En | MEDLINE | ID: mdl-26124555
ABSTRACT
UNLABELLED To manage and intelligently mine the avalanche of genomic sequences intuitive and user-friendly graphical interfaces are required. Here we present BlastXtract2 which exclusively facilitates early exploration of un-annotated genomic and metagenomic sequences. Various formats of translated searches, including the commonly used BlastX, of multiple sequences against multiple protein databases can be uploaded to a relational database server, which can be accessed via a locally installed web-server. There, an intuitive GUI allows straightforward data-mining and enables quick detection of potential frameshifts and poorly sequenced or assembled regions, thereby contributing in making BlastXtract2 a unique and valuable tool for early exploration of (meta)genomic sequences.

AVAILABILITY:

Source code, documentation and an online demo version are available at https//github.com/ ClaessonLab/BlastXtract2.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Bioinformation Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Bioinformation Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda