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Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes.
Zambetti, Noemi A; Bindels, Eric M J; Van Strien, Paulina M H; Valkhof, Marijke G; Adisty, Maria N; Hoogenboezem, Remco M; Sanders, Mathijs A; Rommens, Johanna M; Touw, Ivo P; Raaijmakers, Marc H G P.
Afiliação
  • Zambetti NA; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Bindels EM; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Van Strien PM; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Valkhof MG; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands Current address: Laboratory for Cell Therapy, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands.
  • Adisty MN; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Hoogenboezem RM; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Sanders MA; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Rommens JM; Program in Genetics & Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Department of Molecular Genetics, University of Toronto, ON, Canada.
  • Touw IP; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands.
  • Raaijmakers MH; Department of Hematology, Erasmus Medical Center Cancer Institute, Rotterdam, the Netherlands m.h.g.raaijmakers@erasmusmc.nl.
Haematologica ; 100(10): 1285-93, 2015 Oct.
Article em En | MEDLINE | ID: mdl-26185170

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Proteínas / Diferenciação Celular / Linhagem da Célula / Células Mieloides / Neutropenia Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Haematologica Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Proteínas / Diferenciação Celular / Linhagem da Célula / Células Mieloides / Neutropenia Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Haematologica Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda