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Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope.
Robinson, Luke N; Tharakaraman, Kannan; Rowley, Kirk J; Costa, Vivian V; Chan, Kuan Rong; Wong, Yee Hwa; Ong, Li Ching; Tan, Hwee Cheng; Koch, Tyree; Cain, David; Kirloskar, Rama; Viswanathan, Karthik; Liew, Chong Wai; Tissire, Hamid; Ramakrishnan, Boopathy; Myette, James R; Babcock, Gregory J; Sasisekharan, V; Alonso, Sylvie; Chen, Jianzhu; Lescar, Julien; Shriver, Zachary; Ooi, Eng Eong; Sasisekharan, Ram.
Afiliação
  • Robinson LN; Visterra Inc., One Kendall Square, Suite B3301, Cambridge, MA 02139, USA; Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge MA 02139; USA.
  • Tharakaraman K; Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge MA 02139; USA.
  • Rowley KJ; Visterra Inc., One Kendall Square, Suite B3301, Cambridge, MA 02139, USA.
  • Costa VV; Infectious Diseases Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore.
  • Chan KR; Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, 8 College Road, Singapore 169857.
  • Wong YH; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551.
  • Ong LC; Infectious Diseases Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore.
  • Tan HC; Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, 8 College Road, Singapore 169857.
  • Koch T; Visterra Inc., One Kendall Square, Suite B3301, Cambridge, MA 02139, USA.
  • Cain D; Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge MA 02139; USA.
  • Kirloskar R; Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge MA 02139; USA.
  • Viswanathan K; Visterra Inc., One Kendall Square, Suite B3301, Cambridge, MA 02139, USA.
  • Liew CW; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551.
  • Tissire H; Visterra Inc., One Kendall Square, Suite B3301, Cambridge, MA 02139, USA.
  • Ramakrishnan B; Visterra Inc., One Kendall Square, Suite B3301, Cambridge, MA 02139, USA.
  • Myette JR; Visterra Inc., One Kendall Square, Suite B3301, Cambridge, MA 02139, USA.
  • Babcock GJ; Visterra Inc., One Kendall Square, Suite B3301, Cambridge, MA 02139, USA.
  • Sasisekharan V; Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge MA 02139; USA.
  • Alonso S; Infectious Diseases Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore; Department of Microbiology, National University of Singapore, 5 Science Drive 2, Blk MD4, Level 3, Singapore 117545.
  • Chen J; Infectious Diseases Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore; Department of Biology, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge MA 02139, USA.
  • Lescar J; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551.
  • Shriver Z; Visterra Inc., One Kendall Square, Suite B3301, Cambridge, MA 02139, USA.
  • Ooi EE; Infectious Diseases Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore; Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, 8 College Road, Singapore 169857.
  • Sasisekharan R; Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge MA 02139; USA; Infectious Diseases Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore. Electroni
Cell ; 162(3): 493-504, 2015 Jul 30.
Article em En | MEDLINE | ID: mdl-26189681

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Epitopos Imunodominantes / Dengue / Vírus da Dengue / Anticorpos Neutralizantes Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Epitopos Imunodominantes / Dengue / Vírus da Dengue / Anticorpos Neutralizantes Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2015 Tipo de documento: Article