The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling.

Wang, Chengdong; Kam, Richard Kin Ting; Shi, Weili; Xia, Yin; Chen, Xiongfong; Cao, Ying; Sun, Jianmin; Du, Yanzhi; Lu, Gang; Chen, Zijiang; Chan, Wood Yee; Chan, Sun On; Deng, Yi; Zhao, Hui

Wang, Chengdong; Kam, Richard Kin Ting; Shi, Weili; Xia, Yin; Chen, Xiongfong; Cao, Ying; Sun, Jianmin; Du, Yanzhi; Lu, Gang; Chen, Zijiang; Chan, Wood Yee; Chan, Sun On; Deng, Yi; Zhao, Hui.

Afiliação

Wang C; From the School of Biomedical Sciences and.
Kam RK; From the School of Biomedical Sciences and.
Shi W; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.
Xia Y; From the School of Biomedical Sciences and Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen 518057, China.
Chen X; Advanced Biomedical Computing Center, NCI, National Institutes of Health, Frederick, Maryland 21702.
Cao Y; Model Animal Research Center of Nanjing University and Ministry of Education Key Laboratory of Model Animals for Disease Study, 12 Xuefu Road, Pukou High-Tech Zone, Nanjing 210061, China.
Sun J; Translational Cancer Research and Stem Cell Center, Department of Laboratory Medicine, Lund University, Medicon Village, 22381 Lund, Sweden, and.
Du Y; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 845 Lingshan Road, Shanghai 200135, China.
Lu G; From the School of Biomedical Sciences and Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen 518057, China.
Chen Z; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 845 Lingshan Road, Shanghai 200135, China.
Chan WY; From the School of Biomedical Sciences and Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen 518057, China.
Chan SO; From the School of Biomedical Sciences and Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen 518057, China.
Deng Y; Shenzhen Key Laboratory of Cell Microenvironment, Department of Biology, South University of Science and Technology of China, Shenzhen 518055, China.
Zhao H; From the School of Biomedical Sciences and Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen 518057, China, zhaohui@cuhk.edu.hk.

J Biol Chem ; 290(36): 21925-38, 2015 Sep 04.

Article em En | MEDLINE | ID: mdl-26198637

Assuntos

Proteínas Morfogenéticas Ósseas/metabolismo; Histona Desacetilase 1/metabolismo; Crista Neural/metabolismo; Proteína Proto-Oncogênica c-ets-1/metabolismo; Proteínas de Xenopus/metabolismo; Animais; Proteínas Morfogenéticas Ósseas/genética; Embrião não Mamífero/embriologia; Embrião não Mamífero/metabolismo; Perfilação da Expressão Gênica; Regulação da Expressão Gênica no Desenvolvimento; Técnicas de Silenciamento de Genes; Células HEK293; Histona Desacetilase 1/genética; Humanos; Immunoblotting; Hibridização In Situ; Proteínas Inibidoras de Diferenciação/genética; Proteínas Inibidoras de Diferenciação/metabolismo; Proteínas de Membrana/genética; Proteínas de Membrana/metabolismo; Modelos Genéticos; Mutação; Crista Neural/embriologia; Regiões Promotoras Genéticas/genética; Ligação Proteica; Proto-Oncogene Mas; Proteína Proto-Oncogênica c-ets-1/genética; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Transdução de Sinais/genética; Proteínas de Xenopus/genética; Xenopus laevis/embriologia; Xenopus laevis/genética; Xenopus laevis/metabolismo

Palavras-chave

BMP; ETS transcription factor family; Id3; Xenopus; bone morphogenetic protein (BMP); embryo; histone deacetylase (HDAC); neural crest; signal transduction

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Morfogenéticas Ósseas / Proteínas de Xenopus / Proteína Proto-Oncogênica c-ets-1 / Histona Desacetilase 1 / Crista Neural Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article

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