Homoserine Lactones, Methyl Oligohydroxybutyrates, and Other Extracellular Metabolites of Macroalgae-Associated Bacteria of the Roseobacter Clade: Identification and Functions.
Chembiochem
; 16(14): 2094-107, 2015 Sep 21.
Article
em En
| MEDLINE
| ID: mdl-26212108
ABSTRACT
Twenty-four strains of marine Roseobacter clade bacteria were isolated from macroalgae and investigated for the production of quorum-sensing autoinducers, N-acylhomoserine lactones (AHLs). GC/MS analysis of the extracellular metabolites allowed us to evaluate the release of other small molecules as well. Nineteen strains produced AHLs, ranging from 3-OH-C100-HSL (homoserine lactone) to (2E,11Z)-C182-HSL, but no specific phylogenetic or ecological pattern of individual AHL occurrence was observed when cluster analysis was performed. Other identified compounds included indole, tropone, methyl esters of oligomers of 3-hydroxybutyric acid, and various amides, such as N-9-hexadecenoylalanine methyl ester (9-C161-NAME), a structural analogue of AHLs. Several compounds were tested for their antibacterial and antialgal activity on marine isolates likely to occur in the habitat of the macroalgae. Both AHLs and 9-C161-NAME showed high antialgal activity against Skeletonema costatum, whereas their antibacterial activity was low.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Alga Marinha
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4-Butirolactona
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Roseobacter
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Percepção de Quorum
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Hidroxibutiratos
Tipo de estudo:
Diagnostic_studies
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Risk_factors_studies
Idioma:
En
Revista:
Chembiochem
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Alemanha