Tubular proteinuria is the dominant type of proteinuria in an elderly community population in China.
Int Urol Nephrol
; 47(9): 1541-6, 2015 Sep.
Article
em En
| MEDLINE
| ID: mdl-26216674
ABSTRACT
PURPOSE:
To explore the types of proteinuria in the elderly population in China.METHODS:
Seven hundred and fourteen elderly people (≥ 60 years old) from Tianjin, China, were selected for the study. The albumin-to-creatinine ratio and α1-microglobulin-to-creatinine ratio from morning urine samples were used as indicators of proteinuria. The prevalence of proteinuria was evaluated and the proportion of three different types of proteinuria (mixed, glomerular, and tubular) was assessed in the subjects by analyzing these indicators.RESULTS:
Of the 714 subjects, 29.13 % had elevated ACR and 46.36 % had elevated MCR. The proportion of subjects with either elevated ACR or MCR was 53.78 %. The correlation between MCR and ACR was moderate (r = 0.58, R (2) = 0.34, P < 0.001). Overall, tubular proteinuria was dominant (45.83 %), followed by mixed glomerular and tubular proteinuria (35.68 %), and significantly higher than glomerular proteinuria. A diet high in salt was the independent risk factor for tubular proteinuria; physical activity was the independent risk factor for glomerular proteinuria. The risk of glomerular proteinuria was lower in males than in females, but the risk of tubular proteinuria was higher in males.CONCLUSIONS:
The prevalence of tubular proteinuria was higher than that of glomerular proteinuria, and the risk factors are different, in the elderly in China; therefore, tubular damage markers should get more attention in the overall population.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteinúria
/
Vigilância da População
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Túbulos Renais
Tipo de estudo:
Diagnostic_studies
/
Incidence_studies
/
Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
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Screening_studies
Limite:
Aged
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Female
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Humans
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Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Int Urol Nephrol
Ano de publicação:
2015
Tipo de documento:
Article