MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways.

Srivastava, Sanjeev K; Bhardwaj, Arun; Arora, Sumit; Tyagi, Nikhil; Singh, Seema; Andrews, Joel; McClellan, Steve; Wang, Bin; Singh, Ajay P

Srivastava, Sanjeev K; Bhardwaj, Arun; Arora, Sumit; Tyagi, Nikhil; Singh, Seema; Andrews, Joel; McClellan, Steve; Wang, Bin; Singh, Ajay P.

Afiliação

Srivastava SK; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, 1660 Springhill Avenue, Mobile, AL 36604-1405, USA.
Bhardwaj A; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, 1660 Springhill Avenue, Mobile, AL 36604-1405, USA.
Arora S; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, 1660 Springhill Avenue, Mobile, AL 36604-1405, USA.
Tyagi N; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, 1660 Springhill Avenue, Mobile, AL 36604-1405, USA.
Singh S; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, 1660 Springhill Avenue, Mobile, AL 36604-1405, USA.
Andrews J; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, 1660 Springhill Avenue, Mobile, AL 36604-1405, USA.
McClellan S; Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, 1660 Springhill Avenue, Mobile, AL 36604-1405, USA.
Wang B; Department of Mathematics and Statistics, University of South Alabama, Mobile, AL, USA.
Singh AP; 1] Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, 1660 Springhill Avenue, Mobile, AL 36604-1405, USA [2] Department of Biochemistry and Molecular Biology, College of Medicine, University of South Alabama, Mobile, AL, USA.

Br J Cancer ; 113(4): 660-8, 2015 Aug 11.

Article em En | MEDLINE | ID: mdl-26247574

Assuntos

Apoptose/genética; Caspase 3/genética; Caspase 7/genética; MicroRNAs/genética; Neoplasias Pancreáticas/genética; Transdução de Sinais/genética; Linhagem Celular Tumoral; Núcleo Celular/genética; Citocromos c/genética; Regulação para Baixo/genética; Regulação Neoplásica da Expressão Gênica/genética; Humanos; Potencial da Membrana Mitocondrial/genética; Mitocôndrias/genética; Poli(ADP-Ribose) Polimerase-1; Poli(ADP-Ribose) Polimerases; Proteína X Associada a bcl-2/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Transdução de Sinais / Apoptose / MicroRNAs / Caspase 3 / Caspase 7 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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