Constitutive and Inducible Expression of the rRNA Methylase Gene erm(B) in Campylobacter.
Antimicrob Agents Chemother
; 59(10): 6661-4, 2015 Oct.
Article
em En
| MEDLINE
| ID: mdl-26259800
ABSTRACT
Macrolides are the antimicrobials of choice for treating human campylobacteriosis. The recent emergence of erm(B) in Campylobacter bacteria threatens the utility of this class of antibiotics. Here we report the constitutive and inducible expression of erm(B) in Campylobacter isolates derived from diarrheal patients and food-producing animals. Constitutive expression of erm(B) was associated with insertion and deletion in the regulatory region of the gene, providing the first documentation of the differential expression of erm(B) in Campylobacter bacteria.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Campylobacter
/
Metiltransferases
Idioma:
En
Revista:
Antimicrob Agents Chemother
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Estados Unidos