[Paroxysmal cold hemoglobinuria in a 2-year-old boy]. / Paroxysmale Kältehämoglobinurie bei einem 2jährigen Jungen.

ABSTRACT

We report the case of a two-year-old boy, who presented with two episodes of severe abdominal pain and consecutive macrohematuria after he had been outside the house at very low temperatures. The cause of this was found to be acute hemolytic anemia with hemoglobinuria, induced by a cold reacting Donath-Landsteiner autoantibody. After a few days parameters of hemolysis had normalized, hemoglobin levels were within the normal range after 4 weeks. Eight months later the Donath-Landsteiner autoantibody could not be detected any more, the boy is healthy since then.