Two pools of interneurons in the bulbar region of the cardiovascular center of rats.
Dokl Biol Sci
; 463: 178-82, 2015.
Article
em En
| MEDLINE
| ID: mdl-26335965
ABSTRACT
Wistar rats were subjected to renovascular hypertension. Then, we studied two pools of neurons intranuclear neurons located in projection area of the solitary tract nucleus and reticular, magnocellular, and parvicellular nuclei; and two groups of internuclear neurons, which included both small neurons 50-300 µm(2) in size and large neurons more than 350 µm(2) in size. Immunohistochemical methods with antisera against neuronal nitric oxide synthase, cystathionine-ß-synthase, and heme oxygenase-2 were used. The studies were performed 8, 16, and 24 weeks after the development of renovascular hypertension. We have found that at least two pools of interneurons, intra- and internuclear cells, may be involved in the mechanisms of regulation of hemodynamics. These pools of interneurons differ in some topochemical and functional features, including different resistances to an increased blood pressure.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Bulbo
/
Hipertensão Renovascular
/
Interneurônios
Limite:
Animals
Idioma:
En
Revista:
Dokl Biol Sci
Ano de publicação:
2015
Tipo de documento:
Article