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Multitheragnostic Multi-GNRs Crystal-Seeded Magnetic Nanoseaurchin for Enhanced In Vivo Mesenchymal-Stem-Cell Homing, Multimodal Imaging, and Stroke Therapy.
Chen, Po-Jung; Kang, Yi-Da; Lin, Chen-Huan; Chen, San-Yuan; Hsieh, Chia-Hung; Chen, You-Yin; Chiang, Chun-Wei; Lee, Wei; Hsu, Chung-Y; Liao, Lun-De; Fan, Chih-Tai; Li, Meng-Lin; Shyu, Woei-Cherng.
Afiliação
  • Chen PJ; Department of Materials Science and Engineering, National Chiao Tung University, No. 1001, Ta-Hsueh Rd., Hsinchu, Taiwan, 300, Republic of China.
  • Kang YD; Department of Materials Science and Engineering, National Chiao Tung University, No. 1001, Ta-Hsueh Rd., Hsinchu, Taiwan, 300, Republic of China.
  • Lin CH; Center for Neuropsychiatry and Department of Neurology, China Medical University & Hospital, Taichung, Taiwan, 40447, Republic of China.
  • Chen SY; Department of Materials Science and Engineering, National Chiao Tung University, No. 1001, Ta-Hsueh Rd., Hsinchu, Taiwan, 300, Republic of China.
  • Hsieh CH; Graduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan, 40402, Republic of China.
  • Chen YY; Department of Biomedical Engineering, National Yang Ming University, No.155, Sec. 2, Linong St., Taipei, Taiwan, 112, Republic of China.
  • Chiang CW; Center for Neuropsychiatry and Department of Neurology, China Medical University & Hospital, Taichung, Taiwan, 40447, Republic of China.
  • Lee W; Center for Neuropsychiatry and Department of Neurology, China Medical University & Hospital, Taichung, Taiwan, 40447, Republic of China.
  • Hsu CY; Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan, 40402, Republic of China.
  • Liao LD; Singapore Institute for Neurotechnology (SINAPSE), National University of Singapore, 28 Medical Drive, #05-COR, 117456, Singapore.
  • Fan CT; Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, 35 Keyan Rd., Zhunan Town, Miaoli County, Taiwan, 35053, Republic of China.
  • Li ML; Department of Electrical Engineering, National Tsing Hua University, Hsinchu, Taiwan, 30013, Republic of China.
  • Shyu WC; Department of Electrical Engineering, National Tsing Hua University, Hsinchu, Taiwan, 30013, Republic of China.
Adv Mater ; 27(41): 6488-95, 2015 Nov 04.
Article em En | MEDLINE | ID: mdl-26403165
A multifunctional nanoseaurchin probe in which mesoporous silica nanobeads with iron oxide nanoparticles embedded and multi-gold nanorods crystal-seeded are fabricated and labeled with umbilical cord mesenchymal stem cells through endocytosis. This nanoplatform enables efficient magnetic remote-controlled guiding for stem cell homing, and provides dual modalities of photoacoustic imaging and magnetic resonance imaging for in situ tracking and long-term monitoring to achieve therapeutic efficacy.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acidente Vascular Cerebral / Transplante de Células-Tronco Mesenquimais / Nanotubos / Nanopartículas de Magnetita / Ouro Tipo de estudo: Diagnostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Adv Mater Assunto da revista: BIOFISICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acidente Vascular Cerebral / Transplante de Células-Tronco Mesenquimais / Nanotubos / Nanopartículas de Magnetita / Ouro Tipo de estudo: Diagnostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Adv Mater Assunto da revista: BIOFISICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China