Role of toll-like receptor 4 in melatonin-induced cardioprotection.

Nduhirabandi, Frederic; Lamont, Kim; Albertyn, Zulfah; Opie, Lionel H; Lecour, Sandrine

Nduhirabandi, Frederic; Lamont, Kim; Albertyn, Zulfah; Opie, Lionel H; Lecour, Sandrine.

Afiliação

Nduhirabandi F; Cardioprotection Group, Hatter Institute for Cardiovascular Research in Africa and South African Medical Research Council Inter-University Cape Heart Group, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Lamont K; Cardioprotection Group, Hatter Institute for Cardiovascular Research in Africa and South African Medical Research Council Inter-University Cape Heart Group, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Albertyn Z; Cardioprotection Group, Hatter Institute for Cardiovascular Research in Africa and South African Medical Research Council Inter-University Cape Heart Group, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Opie LH; Cardioprotection Group, Hatter Institute for Cardiovascular Research in Africa and South African Medical Research Council Inter-University Cape Heart Group, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Lecour S; Cardioprotection Group, Hatter Institute for Cardiovascular Research in Africa and South African Medical Research Council Inter-University Cape Heart Group, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

J Pineal Res ; 60(1): 39-47, 2016 Jan.

Article em En | MEDLINE | ID: mdl-26465095

Assuntos

Cardiotônicos/farmacologia; Melatonina/farmacologia; Traumatismo por Reperfusão Miocárdica/prevenção & controle; Transdução de Sinais/efeitos dos fármacos; Receptor 4 Toll-Like/metabolismo; Animais; Masculino; Camundongos; Camundongos Knockout; Traumatismo por Reperfusão Miocárdica/genética; Traumatismo por Reperfusão Miocárdica/metabolismo; Traumatismo por Reperfusão Miocárdica/patologia; Miócitos Cardíacos/metabolismo; Miócitos Cardíacos/patologia; Ratos; Ratos Wistar; Receptores Tipo II do Fator de Necrose Tumoral/genética; Receptores Tipo II do Fator de Necrose Tumoral/metabolismo; Fator de Transcrição STAT3/genética; Fator de Transcrição STAT3/metabolismo; Transdução de Sinais/genética; Sulfonamidas/farmacologia; Receptor 4 Toll-Like/genética; Fator de Necrose Tumoral alfa/genética; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

cardioprotection; ischemia/reperfusion injury; melatonin; survivor activating factor enhancement pathway; toll-like receptor 4

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cardiotônicos / Traumatismo por Reperfusão Miocárdica / Transdução de Sinais / Receptor 4 Toll-Like / Melatonina Limite: Animals Idioma: En Revista: J Pineal Res Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: África do Sul

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