Cost-effectiveness analysis of sacral nerve stimulation as treatment for severe irritable bowel syndrome.
Colorectal Dis
; 18(1): O30-6, 2016 Jan.
Article
em En
| MEDLINE
| ID: mdl-26466156
ABSTRACT
AIM:
Early results from sacral nerve stimulation (SNS) for severe irritable bowel syndrome (IBS) are promising but estimates of cost-effectiveness are lacking. Our object was to perform a cost-effectiveness analysis for SNS as an alternative to no treatment of IBS.METHOD:
This retrospective analysis was based on the results from a randomized controlled crossover study with a cost-utility analysis performed on patient-level data and modelling of censored data over a projected period of time of up to 20 years. The analysis was conducted on an intention-to-treat approach. For estimation of the uncertainty of the incremental cost-effectiveness ratio a bias corrected bootstrap analysis was performed.RESULTS:
Cost-effectiveness was not reached for 4 years after permanent implantation (£31 270 per quality-adjusted life years), which was the upper limit for patient follow-up, but our data imply a cost-effectiveness from a 7-year perspective onwards.CONCLUSION:
The study indicates the SNS treatment for IBS is cost effective from a 7-year perspective onwards.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Terapia por Estimulação Elétrica
/
Análise Custo-Benefício
/
Síndrome do Intestino Irritável
/
Plexo Lombossacral
Tipo de estudo:
Health_economic_evaluation
/
Observational_studies
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Colorectal Dis
Assunto da revista:
GASTROENTEROLOGIA
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Dinamarca