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Evaluation of Normalization Methods To Predict CYP3A4 Induction in Six Fully Characterized Cryopreserved Human Hepatocyte Preparations and HepaRG Cells.
Vermet, Hélène; Raoust, Nathalie; Ngo, Robert; Esserméant, Luc; Klieber, Sylvie; Fabre, Gérard; Boulenc, Xavier.
Afiliação
  • Vermet H; Drug Disposition Domain, Disposition, Safety and Animal Research Scientific Core Platform (H.V., N.R., R.N., S.K., G.F., X.B.); Biostatistics and Programming, Clinical Sciences & Operations, Scientific Core Platform (L.E.), Sanofi Recherche & Développement, Montpellier, France.
  • Raoust N; Drug Disposition Domain, Disposition, Safety and Animal Research Scientific Core Platform (H.V., N.R., R.N., S.K., G.F., X.B.); Biostatistics and Programming, Clinical Sciences & Operations, Scientific Core Platform (L.E.), Sanofi Recherche & Développement, Montpellier, France.
  • Ngo R; Drug Disposition Domain, Disposition, Safety and Animal Research Scientific Core Platform (H.V., N.R., R.N., S.K., G.F., X.B.); Biostatistics and Programming, Clinical Sciences & Operations, Scientific Core Platform (L.E.), Sanofi Recherche & Développement, Montpellier, France.
  • Esserméant L; Drug Disposition Domain, Disposition, Safety and Animal Research Scientific Core Platform (H.V., N.R., R.N., S.K., G.F., X.B.); Biostatistics and Programming, Clinical Sciences & Operations, Scientific Core Platform (L.E.), Sanofi Recherche & Développement, Montpellier, France.
  • Klieber S; Drug Disposition Domain, Disposition, Safety and Animal Research Scientific Core Platform (H.V., N.R., R.N., S.K., G.F., X.B.); Biostatistics and Programming, Clinical Sciences & Operations, Scientific Core Platform (L.E.), Sanofi Recherche & Développement, Montpellier, France.
  • Fabre G; Drug Disposition Domain, Disposition, Safety and Animal Research Scientific Core Platform (H.V., N.R., R.N., S.K., G.F., X.B.); Biostatistics and Programming, Clinical Sciences & Operations, Scientific Core Platform (L.E.), Sanofi Recherche & Développement, Montpellier, France.
  • Boulenc X; Drug Disposition Domain, Disposition, Safety and Animal Research Scientific Core Platform (H.V., N.R., R.N., S.K., G.F., X.B.); Biostatistics and Programming, Clinical Sciences & Operations, Scientific Core Platform (L.E.), Sanofi Recherche & Développement, Montpellier, France xavier.boulenc
Drug Metab Dispos ; 44(1): 50-60, 2016 Jan.
Article em En | MEDLINE | ID: mdl-26467767
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Criopreservação / Hepatócitos / Interações Medicamentosas / Citocromo P-450 CYP3A / Indutores do Citocromo P-450 CYP3A Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: França
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Criopreservação / Hepatócitos / Interações Medicamentosas / Citocromo P-450 CYP3A / Indutores do Citocromo P-450 CYP3A Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: França