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Germ-line variants identified by next generation sequencing in a panel of estrogen and cancer associated genes correlate with poor clinical outcome in Lynch syndrome patients.
Jóri, Balazs; Kamps, Rick; Xanthoulea, Sofia; Delvoux, Bert; Blok, Marinus J; Van de Vijver, Koen K; de Koning, Bart; Oei, Felicia Trups; Tops, Carli M; Speel, Ernst Jm; Kruitwagen, Roy F; Gomez-Garcia, Encarna B; Romano, Andrea.
Afiliação
  • Jóri B; Department of Gynecology and Obstetrics, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Kamps R; Department of Clinical Genetics, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Xanthoulea S; Department of Clinical Genetics, Genomics & Bioinformatics, CARIM - School for Cardiovascular Diseases, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Delvoux B; Department of Gynecology and Obstetrics, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Blok MJ; Department of Gynecology and Obstetrics, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Van de Vijver KK; Department of Clinical Genetics, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • de Koning B; Department of Pathology, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Oei FT; Current address: Divisions of Diagnostic Oncology & Molecular Pathology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, The Netherlands.
  • Tops CM; Department of Clinical Genetics, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Speel EJ; Department of Clinical Genetics, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Kruitwagen RF; Department of Clinical Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
  • Gomez-Garcia EB; Department of Pathology, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
  • Romano A; Department of Gynecology and Obstetrics, GROW - School for Oncology & Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Oncotarget ; 6(38): 41108-22, 2015 Dec 01.
Article em En | MEDLINE | ID: mdl-26517685
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais Hereditárias sem Polipose / Neoplasias do Endométrio / Mutação em Linhagem Germinativa / Estrogênios / Sequenciamento de Nucleotídeos em Larga Escala Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Revista: Oncotarget Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais Hereditárias sem Polipose / Neoplasias do Endométrio / Mutação em Linhagem Germinativa / Estrogênios / Sequenciamento de Nucleotídeos em Larga Escala Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Revista: Oncotarget Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda