Genome-wide studies identify a novel interplay between AML1 and AML1/ETO in t(8;21) acute myeloid leukemia.

Li, Yizhen; Wang, Huanwei; Wang, Xiaoling; Jin, Wen; Tan, Yun; Fang, Hai; Chen, Saijuan; Chen, Zhu; Wang, Kankan

Li, Yizhen; Wang, Huanwei; Wang, Xiaoling; Jin, Wen; Tan, Yun; Fang, Hai; Chen, Saijuan; Chen, Zhu; Wang, Kankan.

Afiliação

Li Y; State Key Laboratory of Medical Genomics and Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;
Wang H; State Key Laboratory of Medical Genomics and Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;
Wang X; State Key Laboratory of Medical Genomics and Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;
Jin W; State Key Laboratory of Medical Genomics and Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;
Tan Y; State Key Laboratory of Medical Genomics and Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;
Fang H; Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China; and.
Chen S; State Key Laboratory of Medical Genomics and Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China; and.
Chen Z; State Key Laboratory of Medical Genomics and Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China; and Sino-French
Wang K; State Key Laboratory of Medical Genomics and Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China; and Sino-French

Blood ; 127(2): 233-42, 2016 Jan 14.

Article em En | MEDLINE | ID: mdl-26546158

Assuntos

Cromossomos Humanos Par 21; Cromossomos Humanos Par 8; Subunidade alfa 2 de Fator de Ligação ao Core/genética; Leucemia Mieloide Aguda/genética; Proteínas de Fusão Oncogênica/genética; Translocação Genética; Cromatina/metabolismo; Subunidade alfa 2 de Fator de Ligação ao Core/metabolismo; Regulação Leucêmica da Expressão Gênica; Genes Dominantes; Estudo de Associação Genômica Ampla; Humanos; Leucemia Mieloide Aguda/metabolismo; Leucemia Mieloide Aguda/patologia; Proteínas de Fusão Oncogênica/metabolismo; Ligação Proteica; Proteína 1 Parceira de Translocação de RUNX1; Fator de Transcrição AP-1/metabolismo; Células Tumorais Cultivadas; Células U937

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Translocação Genética / Cromossomos Humanos Par 8 / Cromossomos Humanos Par 21 / Leucemia Mieloide Aguda / Proteínas de Fusão Oncogênica / Subunidade alfa 2 de Fator de Ligação ao Core Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Blood Ano de publicação: 2016 Tipo de documento: Article

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