Intermittent claudication and limb-threatening ischemia in systemic lupus erythematosus and in SLE-like disease: a report of two cases and review of the literature.
Surgery
; 106(1): 21-5, 1989 Jul.
Article
em En
| MEDLINE
| ID: mdl-2662462
ABSTRACT
Intermittent claudication and limb-threatening ischemia caused by occlusion of large and medium-sized arteries are rare manifestations of systemic lupus erythematosus. So far only eight documented cases have been reported, predominantly in young women. In this report two more patients are described. There is no common opinion concerning pathophysiologic mechanism, but immunologic endothelial damage and circulating antibodies to phospholipid probably play a role. The results of medical and surgical treatment are disappointing, and amputation becomes necessary in more than half of the patients.
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Base de dados:
MEDLINE
Assunto principal:
Claudicação Intermitente
/
Isquemia
/
Lúpus Eritematoso Sistêmico
Tipo de estudo:
Etiology_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Surgery
Ano de publicação:
1989
Tipo de documento:
Article
País de afiliação:
Holanda