[Sustained-release Opioids: Morphine, Oxycodone and Tapentadol].
Masui
; 64(11): 1133-40, 2015 Nov.
Article
em Ja
| MEDLINE
| ID: mdl-26689063
ABSTRACT
Opioid analgesics are widely used for managing moderate to severe pain. In cancer pain management sustained-release opioids are used for continuous pain as well as immediate-release opioids for breakthrough pain. Sustained-release drugs have the advantage of stabilizing the blood concentration, although it takes some time to exert their effects. In Japan, the currently available oral sustained-release opioids include six types of sustained-release morphine (three are once-a-day formulations, while the rest are twice-a-day), one type of oxycodone and tapentadol. In this article, we will discuss the pharmacokinetic properties of MS Contin, Morphes, Kadian, P guard and Pacif as sustained-release morphine, Oxycontin as sustained-release oxycodone and Tapenta as sustained-release tapentadol.
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Base de dados:
MEDLINE
Assunto principal:
Oxicodona
/
Fenóis
/
Analgésicos Opioides
/
Morfina
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
Ja
Revista:
Masui
Ano de publicação:
2015
Tipo de documento:
Article