Uncovering the networks involved in stem cell maintenance and asymmetric cell division in the Arabidopsis root.
Curr Opin Plant Biol
; 29: 38-43, 2016 Feb.
Article
em En
| MEDLINE
| ID: mdl-26707611
ABSTRACT
Stem cells are the source of different cell types and tissues in all multicellular organisms. In plants, the balance between stem cell self-renewal and differentiation of their progeny is crucial for correct tissue and organ formation. How transcriptional programs precisely control stem cell maintenance and identity, and what are the regulatory programs influencing stem cell asymmetric cell division (ACD), are key questions that researchers have sought to address for the past decade. Successful efforts in genetic, molecular, and developmental biology, along with mathematical modeling, have identified some of the players involved in stem cell regulation. In this review, we will discuss several studies that characterized many of the genetic programs and molecular mechanisms regulating stem cell ACD and their identity in the Arabidopsis root. We will also highlight how the growing use of mathematical modeling provides a comprehensive and quantitative perspective on the design rules governing stem cell ACDs.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Células-Tronco
/
Arabidopsis
/
Raízes de Plantas
Idioma:
En
Revista:
Curr Opin Plant Biol
Assunto da revista:
BOTANICA
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Estados Unidos