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Chemotherapy-Induced Intestinal Mucosal Barrier Damage: a Cause of Falsely Elevated Serum 1,3-Beta-d-Glucan Levels?
Prattes, Juergen; Raggam, Reinhard B; Vanstraelen, Kim; Rabensteiner, Jasmin; Hoegenauer, Christoph; Krause, Robert; Prüller, Florian; Wölfler, Albert; Spriet, Isabel; Hoenigl, Martin.
Afiliação
  • Prattes J; Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria Center for Biomarker Research in Medicine, Graz, Austria.
  • Raggam RB; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria martin.hoenigl@medunigraz.at reinhard.raggam@medunigraz.at.
  • Vanstraelen K; Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences University Hospital Leuven, Leuven, Belgium.
  • Rabensteiner J; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
  • Hoegenauer C; Division of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria.
  • Krause R; Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria Center for Biomarker Research in Medicine, Graz, Austria.
  • Prüller F; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
  • Wölfler A; Division of Hematology, Medical University of Graz, Graz, Austria.
  • Spriet I; Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences University Hospital Leuven, Leuven, Belgium.
  • Hoenigl M; Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria Center for Biomarker Research in Medicine, Graz, Austria Division of Infectious Diseases, Department of Medicine, University of California, San Diego, San Diego, California, USA Division of Pulmonology, M
J Clin Microbiol ; 54(3): 798-801, 2016 Mar.
Article em En | MEDLINE | ID: mdl-26719433
Blood citrulline and intestinal fatty acid binding protein were determined as biomarkers for intestinal mucositis. Biomarker levels were correlated with corresponding serum 1,3-beta-D-glucan levels in 56 samples obtained from 33 cases with underlying hematological malignancies receiving induction chemotherapy. No correlation between biomarkers of intestinal mucositis and BDG levels was observed. (This study has been registered at ClinicalTrials.gov under registration no. NCT01576653.).
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mucosite / Mucosa Intestinal / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Microbiol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Áustria
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mucosite / Mucosa Intestinal / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Microbiol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Áustria