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Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-ß-Lactamases and Penicillin-Binding Proteins.
King, Andrew M; King, Dustin T; French, Shawn; Brouillette, Eric; Asli, Abdelhamid; Alexander, J Andrew N; Vuckovic, Marija; Maiti, Samarendra N; Parr, Thomas R; Brown, Eric D; Malouin, François; Strynadka, Natalie C J; Wright, Gerard D.
Afiliação
  • King AM; M.G. DeGroote Institute for Infectious Disease Research, McMaster University , Hamilton, Ontario L8S 4K1, Canada.
  • King DT; The Department of Biochemistry and Molecular Biology and Centre for Blood Research, University of British Columbia . 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
  • French S; M.G. DeGroote Institute for Infectious Disease Research, McMaster University , Hamilton, Ontario L8S 4K1, Canada.
  • Brouillette E; Centre d'Etude et de Valorisation de la Diversité Microbienne (CEVDM), Département de Biologie, Faculté des Sciences, Université de Sherbrooke , Sherbrooke, Quebec, Canada J1K 2R1.
  • Asli A; Centre d'Etude et de Valorisation de la Diversité Microbienne (CEVDM), Département de Biologie, Faculté des Sciences, Université de Sherbrooke , Sherbrooke, Quebec, Canada J1K 2R1.
  • Alexander JA; The Department of Biochemistry and Molecular Biology and Centre for Blood Research, University of British Columbia . 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
  • Vuckovic M; The Department of Biochemistry and Molecular Biology and Centre for Blood Research, University of British Columbia . 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
  • Maiti SN; NAEJA Pharmaceutical, Inc. , Edmonton, Alberta T6E 5V2, Canada.
  • Parr TR; Fedora Pharmaceutical, Inc. , Edmonton, Alberta T6E 5V2, Canada.
  • Brown ED; M.G. DeGroote Institute for Infectious Disease Research, McMaster University , Hamilton, Ontario L8S 4K1, Canada.
  • Malouin F; Centre d'Etude et de Valorisation de la Diversité Microbienne (CEVDM), Département de Biologie, Faculté des Sciences, Université de Sherbrooke , Sherbrooke, Quebec, Canada J1K 2R1.
  • Strynadka NC; The Department of Biochemistry and Molecular Biology and Centre for Blood Research, University of British Columbia . 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
  • Wright GD; M.G. DeGroote Institute for Infectious Disease Research, McMaster University , Hamilton, Ontario L8S 4K1, Canada.
ACS Chem Biol ; 11(4): 864-8, 2016 Apr 15.
Article em En | MEDLINE | ID: mdl-26731698
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Ligação às Penicilinas / Compostos Azabicíclicos / Inibidores de beta-Lactamases Idioma: En Revista: ACS Chem Biol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Ligação às Penicilinas / Compostos Azabicíclicos / Inibidores de beta-Lactamases Idioma: En Revista: ACS Chem Biol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Canadá