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LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function.
Sloan, Max; Alegre-Abarrategui, Javier; Potgieter, Dawid; Kaufmann, Anna-Kristin; Exley, Richard; Deltheil, Thierry; Threlfell, Sarah; Connor-Robson, Natalie; Brimblecombe, Katherine; Wallings, Rebecca; Cioroch, Milena; Bannerman, David M; Bolam, J Paul; Magill, Peter J; Cragg, Stephanie J; Dodson, Paul D; Wade-Martins, Richard.
Afiliação
  • Sloan M; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics.
  • Alegre-Abarrategui J; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics.
  • Potgieter D; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics.
  • Kaufmann AK; Oxford Parkinson's Disease Centre, Medical Research Council Brain Network Dynamics Unit, Department of Pharmacology and.
  • Exley R; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics.
  • Deltheil T; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics.
  • Threlfell S; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics.
  • Connor-Robson N; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics.
  • Brimblecombe K; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics.
  • Wallings R; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics.
  • Cioroch M; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics.
  • Bannerman DM; Department of Experimental Psychology, University of Oxford, Oxford, UK.
  • Bolam JP; Oxford Parkinson's Disease Centre, Medical Research Council Brain Network Dynamics Unit, Department of Pharmacology and.
  • Magill PJ; Oxford Parkinson's Disease Centre, Medical Research Council Brain Network Dynamics Unit, Department of Pharmacology and.
  • Cragg SJ; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics, stephanie.cragg@dpag.ox.ac.uk paul.dodson@pharm.ox.ac.uk richard.wade-martins@dpag.ox.ac.uk.
  • Dodson PD; Oxford Parkinson's Disease Centre, Medical Research Council Brain Network Dynamics Unit, Department of Pharmacology and stephanie.cragg@dpag.ox.ac.uk paul.dodson@pharm.ox.ac.uk richard.wade-martins@dpag.ox.ac.uk.
  • Wade-Martins R; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics, stephanie.cragg@dpag.ox.ac.uk paul.dodson@pharm.ox.ac.uk richard.wade-martins@dpag.ox.ac.uk.
Hum Mol Genet ; 25(5): 951-63, 2016 Mar 01.
Article em En | MEDLINE | ID: mdl-26744332

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Envelhecimento / Levodopa / Neurônios Dopaminérgicos / Serina-Treonina Proteína Quinase-2 com Repetições Ricas em Leucina / Mutação / Antiparkinsonianos Limite: Animals / Female / Humans / Male Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Envelhecimento / Levodopa / Neurônios Dopaminérgicos / Serina-Treonina Proteína Quinase-2 com Repetições Ricas em Leucina / Mutação / Antiparkinsonianos Limite: Animals / Female / Humans / Male Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2016 Tipo de documento: Article