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It's difficult, but important, to make negative predictions.
Williams, Richard V; Amberg, Alexander; Brigo, Alessandro; Coquin, Laurence; Giddings, Amanda; Glowienke, Susanne; Greene, Nigel; Jolly, Robert; Kemper, Ray; O'Leary-Steele, Catherine; Parenty, Alexis; Spirkl, Hans-Peter; Stalford, Susanne A; Weiner, Sandy K; Wichard, Joerg.
Afiliação
  • Williams RV; Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Leeds, LS11 5PS, UK. Electronic address: richard.williams@lhasalimited.org.
  • Amberg A; Sanofi-Aventis Deutschland GmbH, R&D DSAR/Preclinical Safety FF, Industriepark Hoechst, Bldg. H823, D-65926 Frankfurt am Main, Germany.
  • Brigo A; Roche Pharmaceutical Research & Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Grenzacherstrasse 124, CH-4070 Basel, Switzerland.
  • Coquin L; Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Leeds, LS11 5PS, UK.
  • Giddings A; GlaxoSmithKline Pre-Clinical Development, Park Road, Ware, Hertfordshire SG12 0DP, UK.
  • Glowienke S; Novartis Pharma AG, Pre-clinical Safety, Werk Klybeck, CH-4057 Basel, Switzerland.
  • Greene N; Compound Safety Prediction, Pfizer Global Research & Development, 558 Eastern Point Road, Groton, CT 06340, USA.
  • Jolly R; Health/Safety/Environmental, Lilly Research Laboratories, Indianapolis, IN, USA.
  • Kemper R; Vertex Pharmaceuticals Incorporated, 50 Northern Ave, Boston MA, USA.
  • O'Leary-Steele C; Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Leeds, LS11 5PS, UK.
  • Parenty A; Novartis Pharma AG, Pre-clinical Safety, Werk Klybeck, CH-4057 Basel, Switzerland.
  • Spirkl HP; Sanofi-Aventis Deutschland GmbH, R&D DSAR/Preclinical Safety FF, Industriepark Hoechst, Bldg. H823, D-65926 Frankfurt am Main, Germany.
  • Stalford SA; Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Leeds, LS11 5PS, UK.
  • Weiner SK; Janssen Research & Development, 1400 McKean Road, Spring House, PA 19477, USA.
  • Wichard J; Bayer Pharma AG, Investigational Toxicology, Muellerstr. 178, S 116, D-13353, Berlin, Germany.
Regul Toxicol Pharmacol ; 76: 79-86, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26785392
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Simulação por Computador / DNA Bacteriano / Modelos Moleculares / Mutagênese / Relação Quantitativa Estrutura-Atividade / Testes de Mutagenicidade / Mutação Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Regul Toxicol Pharmacol Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Simulação por Computador / DNA Bacteriano / Modelos Moleculares / Mutagênese / Relação Quantitativa Estrutura-Atividade / Testes de Mutagenicidade / Mutação Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Regul Toxicol Pharmacol Ano de publicação: 2016 Tipo de documento: Article