Quantifying the chameleonic properties of macrocycles and other high-molecular-weight drugs.

Whitty, Adrian; Zhong, Mengqi; Viarengo, Lauren; Beglov, Dmitri; Hall, David R; Vajda, Sandor

Whitty, Adrian; Zhong, Mengqi; Viarengo, Lauren; Beglov, Dmitri; Hall, David R; Vajda, Sandor.

Afiliação

Whitty A; Department of Chemistry, Boston University, Boston, MA, USA. Electronic address: whitty@bu.edu.
Zhong M; Department of Chemistry, Boston University, Boston, MA, USA.
Viarengo L; Department of Chemistry, Boston University, Boston, MA, USA.
Beglov D; Departments of Biomedical Engineering and Chemistry, Boston University, Boston, MA, USA.
Hall DR; Acpharis Inc., Holliston, MA, USA.
Vajda S; Department of Chemistry, Boston University, Boston, MA, USA; Departments of Biomedical Engineering and Chemistry, Boston University, Boston, MA, USA. Electronic address: Vajda@bu.edu.

Drug Discov Today ; 21(5): 712-7, 2016 05.

Article em En | MEDLINE | ID: mdl-26891978

Assuntos

Compostos Macrocíclicos/química; Desenho de Fármacos; Humanos; Compostos Macrocíclicos/farmacologia; Modelos Moleculares; Peso Molecular

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Macrocíclicos Limite: Humans Idioma: En Revista: Drug Discov Today Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2016 Tipo de documento: Article

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