IDO1 Deficiency Does Not Affect Disease in Mouse Models of Systemic Juvenile Idiopathic Arthritis and Secondary Hemophagocytic Lymphohistiocytosis.

Put, Karen; Brisse, Ellen; Avau, Anneleen; Imbrechts, Maya; Mitera, Tania; Janssens, Rik; Proost, Paul; Fallarino, Francesca; Wouters, Carine H; Matthys, Patrick

Put, Karen; Brisse, Ellen; Avau, Anneleen; Imbrechts, Maya; Mitera, Tania; Janssens, Rik; Proost, Paul; Fallarino, Francesca; Wouters, Carine H; Matthys, Patrick.

Afiliação

Put K; Laboratory of Immunobiology, Rega-Institute for Medical Research, Department of Immunology and Microbiology, KU Leuven - University of Leuven, Leuven, Belgium.
Brisse E; Laboratory of Immunobiology, Rega-Institute for Medical Research, Department of Immunology and Microbiology, KU Leuven - University of Leuven, Leuven, Belgium.
Avau A; Laboratory of Immunobiology, Rega-Institute for Medical Research, Department of Immunology and Microbiology, KU Leuven - University of Leuven, Leuven, Belgium.
Imbrechts M; Laboratory of Immunobiology, Rega-Institute for Medical Research, Department of Immunology and Microbiology, KU Leuven - University of Leuven, Leuven, Belgium.
Mitera T; Laboratory of Immunobiology, Rega-Institute for Medical Research, Department of Immunology and Microbiology, KU Leuven - University of Leuven, Leuven, Belgium.
Janssens R; Laboratory of Molecular Immunology, Rega-Institute for Medical Research, Department of Immunology and Microbiology, KU Leuven - University of Leuven, Leuven, Belgium.
Proost P; Laboratory of Molecular Immunology, Rega-Institute for Medical Research, Department of Immunology and Microbiology, KU Leuven - University of Leuven, Leuven, Belgium.
Fallarino F; Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy.
Wouters CH; Laboratory of Pediatric Immunology, University Hospitals Leuven, KU Leuven - University of Leuven, Leuven, Belgium.
Matthys P; Laboratory of Immunobiology, Rega-Institute for Medical Research, Department of Immunology and Microbiology, KU Leuven - University of Leuven, Leuven, Belgium.

PLoS One ; 11(2): e0150075, 2016.

Article em En | MEDLINE | ID: mdl-26914138

Assuntos

Artrite Experimental/genética; Artrite Juvenil/patologia; Citocinas/sangue; Indolamina-Pirrol 2,3,-Dioxigenase/genética; Linfo-Histiocitose Hemofagocítica/patologia; Linfócitos T/imunologia; Animais; Apoptose/imunologia; Artrite Experimental/imunologia; Artrite Juvenil/genética; Proliferação de Células; Citomegalovirus/imunologia; Infecções por Citomegalovirus/imunologia; Infecções por Citomegalovirus/patologia; Adjuvante de Freund/imunologia; Indolamina-Pirrol 2,3,-Dioxigenase/metabolismo; Inflamação/imunologia; Interferon gama/genética; Interferon gama/imunologia; Interferon gama/metabolismo; Linfo-Histiocitose Hemofagocítica/genética; Síndrome de Ativação Macrofágica/genética; Síndrome de Ativação Macrofágica/patologia; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C57BL; Camundongos Knockout; Triptofano Oxigenase/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Experimental / Artrite Juvenil / Linfócitos T / Citocinas / Linfo-Histiocitose Hemofagocítica / Indolamina-Pirrol 2,3,-Dioxigenase Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Bélgica

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