The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane.

Guo, Deng-Fu; Cui, Huxing; Zhang, Qihong; Morgan, Donald A; Thedens, Daniel R; Nishimura, Darryl; Grobe, Justin L; Sheffield, Val C; Rahmouni, Kamal

Guo, Deng-Fu; Cui, Huxing; Zhang, Qihong; Morgan, Donald A; Thedens, Daniel R; Nishimura, Darryl; Grobe, Justin L; Sheffield, Val C; Rahmouni, Kamal.

Afiliação

Guo DF; Department of Pharmacology, University of Iowa, Iowa City, Iowa, United States of America.
Cui H; Department of Pharmacology, University of Iowa, Iowa City, Iowa, United States of America.
Zhang Q; Department of Pediatrics, University of Iowa, Iowa City, Iowa, United States of America.
Morgan DA; Department of Pharmacology, University of Iowa, Iowa City, Iowa, United States of America.
Thedens DR; Department of Radiology, University of Iowa, Iowa City, Iowa, United States of America.
Nishimura D; Department of Pediatrics, University of Iowa, Iowa City, Iowa, United States of America.
Grobe JL; Department of Pharmacology, University of Iowa, Iowa City, Iowa, United States of America.
Sheffield VC; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, United States of America.
Rahmouni K; Department of Pediatrics, University of Iowa, Iowa City, Iowa, United States of America.

PLoS Genet ; 12(2): e1005890, 2016 Feb.

Article em En | MEDLINE | ID: mdl-26926121

Assuntos

Síndrome de Bardet-Biedl/metabolismo; Membrana Celular/metabolismo; Receptores para Leptina/metabolismo; Animais; Síndrome de Bardet-Biedl/genética; Membrana Celular/genética; Metabolismo Energético/fisiologia; Feminino; Hipotálamo/fisiologia; Camundongos Mutantes; Camundongos Transgênicos; Proteínas Associadas aos Microtúbulos/genética; Proteínas Associadas aos Microtúbulos/metabolismo; Complexos Multiproteicos/metabolismo; Obesidade/genética; Obesidade/metabolismo; Transporte Proteico; Receptores para Leptina/genética; Proteínas Supressoras de Tumor/genética; Proteínas Supressoras de Tumor/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Membrana Celular / Síndrome de Bardet-Biedl / Receptores para Leptina Limite: Animals Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

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