The minimum effective concentration (MEC90 ) of ropivacaine for ultrasound-guided supraclavicular brachial plexus block.
Anaesthesia
; 71(6): 700-5, 2016 06.
Article
em En
| MEDLINE
| ID: mdl-26945818
ABSTRACT
The aim of this study was to determine the minimum effective concentration of ropivacaine for ultrasound-guided supraclavicular brachial plexus block. Fifty-one patients undergoing arm surgery received double-injection ultrasound-guided supraclavicular block using ropivacaine 40 ml. The concentration of ropivacaine administered to each patient started at 0.225% and then depended on the response of the previous one, based on a biased coin design up-and-down sequential method. In case of failure, the ropivacaine concentration was increased by 0.025% w/v in the next subject. In the case of a successful block, the next patient was randomised to the same concentration or a concentration 0.025% w/v less. Success was defined as complete sensory blockade of the brachial plexus 30 min after the block together with pain-free surgery. The minimum effective ropivacaine concentration in 90% of subjects was 0.257% w/v (95% CI 0.241-0.280%).
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ultrassonografia de Intervenção
/
Bloqueio do Plexo Braquial
/
Amidas
/
Anestésicos Locais
Tipo de estudo:
Clinical_trials
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Anaesthesia
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
China