Exclusive Breast-feeding Protects against Mother-to-Child Transmission of HIV-1 through 12 Months of Age in Tanzania.
J Trop Pediatr
; 62(4): 301-7, 2016 08.
Article
em En
| MEDLINE
| ID: mdl-26999011
ABSTRACT
The jury on transmission of HIV through breast-feeding is still on. Data from a clinical trial in children born to HIV-positive mothers were evaluated with respect to their relationship to mother-to-child transmission. A total of 1629 infants who were not infected at age 6 weeks, had HIV results available at 12 months and who were breast-fed were included in this study. Exclusive breast feeding (EBF) rates declined from 85% at 2 months to < 30% by 4 months. EBF was associated with a sustained and significant reduction in HIV infection. With every incremental month of EBF, HIV infection was reduced by 16% [multivariable (risk ratio) RR 0.84, CI 0.72-0.98, p = 0.03] from enrollment to 6 months of age and by 18% (multivariable RR 0.82, CI 0.72-0.94, p = 0.005) from enrollment to 12 months of age. EBF significantly reduces the risk of vertical HIV transmission through 12 months of age.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Complicações Infecciosas na Gravidez
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Aleitamento Materno
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Infecções por HIV
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HIV-1
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Transmissão Vertical de Doenças Infecciosas
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Lamivudina
/
Leite Humano
Tipo de estudo:
Clinical_trials
Limite:
Adult
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Female
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Humans
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Infant
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Male
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Newborn
/
Pregnancy
País/Região como assunto:
Africa
Idioma:
En
Revista:
J Trop Pediatr
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Tanzânia