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The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation.
Aylon, Yael; Gershoni, Anat; Rotkopf, Ron; Biton, Inbal E; Porat, Ziv; Koh, Anna P; Sun, Xiaochen; Lee, Youngmin; Fiel, Maria-Isabel; Hoshida, Yujin; Friedman, Scott L; Johnson, Randy L; Oren, Moshe.
Afiliação
  • Aylon Y; Department of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot 76100, Israel;
  • Gershoni A; Department of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot 76100, Israel;
  • Rotkopf R; Bioinformatics Unit, Faculty of Biological Services, The Weizmann Institute of Science, Rehovot 76100, Israel;
  • Biton IE; Department of Veterinary Resources, Faculty of Biology, The Weizmann Institute of Science, Rehovot 76100, Israel;
  • Porat Z; Flow Cytometry Unit, Biological Services Department, The Weizmann Institute of Science, Rehovot 76100, Israel;
  • Koh AP; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA;
  • Sun X; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA;
  • Lee Y; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA;
  • Fiel MI; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA;
  • Hoshida Y; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA;
  • Friedman SL; Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA;
  • Johnson RL; Department of Biochemistry and Molecular Biology, Division of Basic Science Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
  • Oren M; Department of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot 76100, Israel;
Genes Dev ; 30(7): 786-97, 2016 Apr 01.
Article em En | MEDLINE | ID: mdl-27013235
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Serina-Treonina Quinases / Proteínas Supressoras de Tumor / Proteína de Ligação a Elemento Regulador de Esterol 2 / Fígado Gorduroso Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Genes Dev Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Serina-Treonina Quinases / Proteínas Supressoras de Tumor / Proteína de Ligação a Elemento Regulador de Esterol 2 / Fígado Gorduroso Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Genes Dev Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2016 Tipo de documento: Article