Muscle biopsies from human muscle diseases with myopathic pathology reveal common alterations in mitochondrial function.

Sunitha, Balaraju; Gayathri, Narayanappa; Kumar, Manish; Keshava Prasad, Thottethodi Subrahmanya; Nalini, Atchayaram; Padmanabhan, Balasundaram; Srinivas Bharath, Muchukunte Mukunda

Sunitha, Balaraju; Gayathri, Narayanappa; Kumar, Manish; Keshava Prasad, Thottethodi Subrahmanya; Nalini, Atchayaram; Padmanabhan, Balasundaram; Srinivas Bharath, Muchukunte Mukunda.

Afiliação

Sunitha B; Department of Neurochemistry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.
Gayathri N; Department of Neuropathology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.
Kumar M; Department of Neuropathology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.
Keshava Prasad TS; Institute of Bioinformatics, Whitefield, Bangalore, Karnataka, India.
Nalini A; Institute of Bioinformatics, Whitefield, Bangalore, Karnataka, India.
Padmanabhan B; NIMHANS-IOB Proteomics and Bioinformatics Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.
Srinivas Bharath MM; YU-IOB Center for Systems Biology and Molecular Medicine, Yenepoya University, Mangalore, India.

J Neurochem ; 138(1): 174-91, 2016 07.

Article em En | MEDLINE | ID: mdl-27015874

Assuntos

Mitocôndrias/metabolismo; Mitocôndrias/patologia; Proteínas Mitocondriais/metabolismo; Músculos/ultraestrutura; Doenças Musculares/patologia; Difosfato de Adenosina/metabolismo; Trifosfato de Adenosina/metabolismo; Adolescente; Adulto; Idoso; Aspartato Aminotransferases/metabolismo; Biópsia; Criança; Citrato (si)-Sintase/metabolismo; Feminino; Humanos; Malato Desidrogenase/metabolismo; Masculino; Pessoa de Meia-Idade; Modelos Moleculares; Complexos Multienzimáticos/metabolismo; Músculos/patologia; Superóxido Dismutase/metabolismo; Triptofano/metabolismo; Adulto Jovem

Palavras-chave

human; mitochondria; muscle; myopathy; proteomics; tryptophan oxidation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Mitocondriais / Mitocôndrias / Músculos / Doenças Musculares Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Revista: J Neurochem Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Índia

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