Review: Ras GTPases and myosin: Qualitative conservation and quantitative diversification in signal and energy transduction.

Mueller, Matthias P; Goody, Roger S

Mueller, Matthias P; Goody, Roger S.

Afiliação

Mueller MP; Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, Dortmund, 44227, Germany.
Goody RS; Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, Dortmund, 44227, Germany.

Biopolymers ; 105(8): 422-30, 2016 Aug.

Article em En | MEDLINE | ID: mdl-27018658

RESUMO

Most GTPases and many ATPases belong to the P-loop class of proteins with significant structural and mechanistic similarities. Here we compare and contrast the basic properties of the Ras family GTPases and myosin, and conclude that there are fundamental similarities but also distinct differences related to their specific roles. © 2016 Wiley Periodicals, Inc. Biopolymers 105: 422-430, 2016.

Assuntos

Metabolismo Energético/fisiologia; Miosinas; Proteínas ras; Animais; Humanos; Miosinas/química; Miosinas/metabolismo; Estrutura Secundária de Proteína; Relação Estrutura-Atividade; Proteínas ras/química; Proteínas ras/metabolismo

Palavras-chave

P-loop; Ras GTPases; myosin; switch I; switch II

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Miosinas / Proteínas ras / Metabolismo Energético Tipo de estudo: Qualitative_research Limite: Animals / Humans Idioma: En Revista: Biopolymers Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha

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