Anal Canal Carcinoma in a Child With Disorders of Sex Development.
Pediatr Blood Cancer
; 63(7): 1293-5, 2016 07.
Article
em En
| MEDLINE
| ID: mdl-27037640
Squamous cell carcinoma of the anal canal in children is rare. To date, the etiology and outcome of this condition have been not fully understood. Here, we report an 11-year-old child with anal canal cancer who had concomitant disorders of sex development. Radiotherapy followed by salvage surgery achieved disease-free survival of 3 years. Since overexpression of cell cycle regulatory protein p16 was immunohistochemically evident in tumor tissue, human papillomavirus infection was considered as a causative factor in the carcinogenesis.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias do Ânus
/
Transtornos do Desenvolvimento Sexual
/
Carcinoma de Células Escamosas
Limite:
Child
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Humans
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Male
Idioma:
En
Revista:
Pediatr Blood Cancer
Assunto da revista:
HEMATOLOGIA
/
NEOPLASIAS
/
PEDIATRIA
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Japão