Dual-Energy Computed Tomography of the Knee, Ankle, and Foot: Noninvasive Diagnosis of Gout and Quantification of Monosodium Urate in Tendons and Ligaments.
Semin Musculoskelet Radiol
; 20(1): 130-6, 2016 Feb.
Article
em En
| MEDLINE
| ID: mdl-27077593
ABSTRACT
Gout is a true crystal deposition arthropathy caused by the precipitation of monosodium urate into joints and periarticular soft tissues. It is the most common inflammatory arthropathy in men and women of older age with a male-to-female ratio of 3 to 81. The disease may progress from asymptomatic hyperuricemia through symptomatic acute gout attacks with asymptomatic periods into chronic symptomatic tophaceous gout. Although invasive arthrocentesis and demonstration of monosodium urate crystals on polarized light microscopy is definitive for the diagnosis of gout, dual-energy computed tomography (CT) allows for noninvasive visualization and reproducible volume quantification of monosodium urate crystals. Based on the high diagnostic performance, dual-energy CT has been included in the 2015 American College of Rheumatology/European League Against Rheumatism Collaborative Initiative Classification Criteria for Gout. Increasing evidence indicates the usefulness of dual-energy CT to guide the management of patients with suspected gout and monitor the effectiveness of urate-lowering medical therapy.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ácido Úrico
/
Tomografia Computadorizada por Raios X
/
Pé
/
Gota
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Articulação do Joelho
/
Articulação do Tornozelo
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Semin Musculoskelet Radiol
Assunto da revista:
FISIOLOGIA
/
ORTOPEDIA
/
RADIOLOGIA
Ano de publicação:
2016
Tipo de documento:
Article