The Value of Circulating Biomarkers in Bicuspid Aortic Valve-Associated Aortopathy.
Thorac Cardiovasc Surg
; 66(4): 278-286, 2018 06.
Article
em En
| MEDLINE
| ID: mdl-27148933
ABSTRACT
Traditional risk stratification model of bicuspid aortic valve (BAV) aortopathy is based on measurement of maximal cross-sectional aortic diameter, definition of proximal aortic shape, and aortic stiffness/elasticity parameters. However, conventional imaging-based criteria are unable to provide reliable information regarding the risk stratification in BAV aortopathy, especially considering the heterogeneous nature of BAV disease. Given those limitations of conventional imaging, there is a growing clinical interest to use circulating biomarkers in the screening process for thoracic aortic aneurysms as well as in the risk-assessment algorithms. We aimed to systematically review currently available biomarkers, which may be of value to predict the natural evolution of aortopathy in individuals with BAV.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Aorta
/
Aneurisma Aórtico
/
Valva Aórtica
/
Biomarcadores
/
Doenças das Valvas Cardíacas
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Thorac Cardiovasc Surg
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Alemanha