Downregulation of B-cell lymphoma/leukemia-2 by overexpressed microRNA 34a enhanced titanium dioxide nanoparticle-induced autophagy in BEAS-2B cells.

Bai, Wenlin; Chen, Yujiao; Sun, Pengling; Gao, Ai

Bai, Wenlin; Chen, Yujiao; Sun, Pengling; Gao, Ai.

Afiliação

Bai W; Department of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, People's Republic of China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing, People's Republic of China.
Chen Y; Department of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, People's Republic of China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing, People's Republic of China.
Sun P; Department of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, People's Republic of China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing, People's Republic of China.
Gao A; Department of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, People's Republic of China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing, People's Republic of China.

Int J Nanomedicine ; 11: 1959-71, 2016.

Article em En | MEDLINE | ID: mdl-27226226

Assuntos

Autofagia/efeitos dos fármacos; MicroRNAs/genética; Nanopartículas/toxicidade; Proteínas Proto-Oncogênicas c-bcl-2/genética; Titânio/toxicidade; Apoptose/efeitos dos fármacos; Brônquios/citologia; Regulação para Baixo/efeitos dos fármacos; Células Epiteliais/efeitos dos fármacos; Regulação da Expressão Gênica/efeitos dos fármacos; Humanos; MicroRNAs/efeitos dos fármacos; Microscopia Eletrônica de Transmissão; Proteínas Associadas aos Microtúbulos/metabolismo; Nanopartículas/química; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo; Transfecção

Palavras-chave

Bcl-2; autophagy; cell death; cytotoxicity; lentivirus; miR34a; titanium dioxide nanoparticles

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Titânio / Proteínas Proto-Oncogênicas c-bcl-2 / MicroRNAs / Nanopartículas Limite: Humans Idioma: En Revista: Int J Nanomedicine Ano de publicação: 2016 Tipo de documento: Article

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