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Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologies.
Maurer, Christine K; Fruth, Martina; Empting, Martin; Avrutina, Olga; Hoßmann, Jörn; Nadmid, Suvd; Gorges, Jan; Herrmann, Jennifer; Kazmaier, Uli; Dersch, Petra; Müller, Rolf; Hartmann, Rolf W.
Afiliação
  • Maurer CK; Department of Drug Design & Optimization, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarland University, Campus E8.1, 66123 Saarbrücken, Germany.
  • Fruth M; German Centre for Infection Research (DZIF), PartnerSite Hannover-Braunschweig, 30625 Hannover, Germany.
  • Empting M; Department of Drug Design & Optimization, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarland University, Campus E8.1, 66123 Saarbrücken, Germany.
  • Avrutina O; German Centre for Infection Research (DZIF), PartnerSite Hannover-Braunschweig, 30625 Hannover, Germany.
  • Hoßmann J; Department of Drug Design & Optimization, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarland University, Campus E8.1, 66123 Saarbrücken, Germany.
  • Nadmid S; German Centre for Infection Research (DZIF), PartnerSite Hannover-Braunschweig, 30625 Hannover, Germany.
  • Gorges J; Clemens-Schöpf-Institute for Organic Chemistry & Biochemistry, Technical University Darmstadt, Alarich-Weiss Straße 4, 64287 Darmstadt, Germany.
  • Herrmann J; German Centre for Infection Research (DZIF), PartnerSite Hannover-Braunschweig, 30625 Hannover, Germany.
  • Kazmaier U; Department of Molecular Infection Biology, Helmholtz Centre for Infection Research (HZI), Inhoffenstraße 7, 38124 Braunschweig, Germany.
  • Dersch P; German Centre for Infection Research (DZIF), PartnerSite Hannover-Braunschweig, 30625 Hannover, Germany.
  • Müller R; Department of Microbial Natural Products, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarland University, Campus E8.1, 66123 Saarbrücken, Germany.
  • Hartmann RW; Institute of Organic Chemistry I, Saarland University, Campus C4.2, 66123 Saarbrücken, Germany.
Future Med Chem ; 8(9): 931-47, 2016 06.
Article em En | MEDLINE | ID: mdl-27253623
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Proteínas Repressoras / RNA / Ácidos Nucleicos / Proteínas de Ligação a RNA / Proteínas de Escherichia coli / Avaliação Pré-Clínica de Medicamentos / Bibliotecas de Moléculas Pequenas Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Revista: Future Med Chem Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Proteínas Repressoras / RNA / Ácidos Nucleicos / Proteínas de Ligação a RNA / Proteínas de Escherichia coli / Avaliação Pré-Clínica de Medicamentos / Bibliotecas de Moléculas Pequenas Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Revista: Future Med Chem Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha