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Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial.
Atkins, Harold L; Bowman, Marjorie; Allan, David; Anstee, Grizel; Arnold, Douglas L; Bar-Or, Amit; Bence-Bruckler, Isabelle; Birch, Paul; Bredeson, Christopher; Chen, Jacqueline; Fergusson, Dean; Halpenny, Mike; Hamelin, Linda; Huebsch, Lothar; Hutton, Brian; Laneuville, Pierre; Lapierre, Yves; Lee, Hyunwoo; Martin, Lisa; McDiarmid, Sheryl; O'Connor, Paul; Ramsay, Timothy; Sabloff, Mitchell; Walker, Lisa; Freedman, Mark S.
Afiliação
  • Atkins HL; Ottawa Hospital Research Institute, Ottawa, ON, Canada; The Ottawa Hospital Blood and Marrow Transplant Program, Ottawa, ON, Canada; Department of Medicine, University of Ottawa, Ottawa, ON, Canada. Electronic address: hatkins@ohri.ca.
  • Bowman M; Ottawa Hospital Research Institute, Ottawa, ON, Canada; The Ottawa Hospital MS Clinic, Ottawa, ON, Canada.
  • Allan D; Ottawa Hospital Research Institute, Ottawa, ON, Canada; The Ottawa Hospital Blood and Marrow Transplant Program, Ottawa, ON, Canada; Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Anstee G; The Ottawa Hospital Blood and Marrow Transplant Program, Ottawa, ON, Canada.
  • Arnold DL; Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montréal, QC, Canada; NeuroRx Research, Montreal, QC, Canada.
  • Bar-Or A; Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montréal, QC, Canada; Neuroimmunology Unit, Montreal Neurological Institute and Hospital, McGill University, Montréal, QC, Canada.
  • Bence-Bruckler I; The Ottawa Hospital Blood and Marrow Transplant Program, Ottawa, ON, Canada; Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Birch P; Ottawa Stem Cell Program, Canadian Blood Services, Ottawa, ON, Canada.
  • Bredeson C; Ottawa Hospital Research Institute, Ottawa, ON, Canada; The Ottawa Hospital Blood and Marrow Transplant Program, Ottawa, ON, Canada; Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Chen J; Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montréal, QC, Canada; Department of Neurosciences, Cleveland Clinic, Cleveland, OH, USA.
  • Fergusson D; Ottawa Hospital Research Institute, Ottawa, ON, Canada; Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Halpenny M; Ottawa Stem Cell Program, Canadian Blood Services, Ottawa, ON, Canada.
  • Hamelin L; The Ottawa Hospital Blood and Marrow Transplant Program, Ottawa, ON, Canada.
  • Huebsch L; The Ottawa Hospital Blood and Marrow Transplant Program, Ottawa, ON, Canada; Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Hutton B; Ottawa Hospital Research Institute, Ottawa, ON, Canada.
  • Laneuville P; McGill University Health Center, Montreal, QC, Canada; Division of Oncology, Department of Medicine, McGill University, Montreal, QC, Canada.
  • Lapierre Y; Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montréal, QC, Canada.
  • Lee H; Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montréal, QC, Canada.
  • Martin L; Ottawa Stem Cell Program, Canadian Blood Services, Ottawa, ON, Canada.
  • McDiarmid S; The Ottawa Hospital Blood and Marrow Transplant Program, Ottawa, ON, Canada.
  • O'Connor P; Division of Neurology, St Michael's Hospital, University of Toronto, Toronto, ON, Canada.
  • Ramsay T; Ottawa Hospital Research Institute, Ottawa, ON, Canada; Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Sabloff M; The Ottawa Hospital Blood and Marrow Transplant Program, Ottawa, ON, Canada; Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
  • Walker L; School of Psychology, University of Ottawa, Ottawa, ON, Canada; The Ottawa Hospital MS Clinic, Ottawa, ON, Canada.
  • Freedman MS; Ottawa Hospital Research Institute, Ottawa, ON, Canada; Department of Medicine, University of Ottawa, Ottawa, ON, Canada; The Ottawa Hospital MS Clinic, Ottawa, ON, Canada.
Lancet ; 388(10044): 576-85, 2016 Aug 06.
Article em En | MEDLINE | ID: mdl-27291994
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transplante de Células-Tronco Hematopoéticas / Imunossupressores / Esclerose Múltipla Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transplante de Células-Tronco Hematopoéticas / Imunossupressores / Esclerose Múltipla Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Ano de publicação: 2016 Tipo de documento: Article