Toward Community Standards and Software for Whole-Cell Modeling.
IEEE Trans Biomed Eng
; 63(10): 2007-14, 2016 10.
Article
em En
| MEDLINE
| ID: mdl-27305665
ABSTRACT
OBJECTIVE:
Whole-cell (WC) modeling is a promising tool for biological research, bioengineering, and medicine. However, substantial work remains to create accurate comprehensive models of complex cells.METHODS:
We organized the 2015 Whole-Cell Modeling Summer School to teach WC modeling and evaluate the need for new WC modeling standards and software by recoding a recently published WC model in the Systems Biology Markup Language.RESULTS:
Our analysis revealed several challenges to representing WC models using the current standards.CONCLUSION:
We, therefore, propose several new WC modeling standards, software, and databases.SIGNIFICANCE:
We anticipate that these new standards and software will enable more comprehensive models.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Simulação por Computador
/
Software
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Biologia de Sistemas
/
Modelos Biológicos
Tipo de estudo:
Prognostic_studies
Limite:
Female
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Humans
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Male
Idioma:
En
Revista:
IEEE Trans Biomed Eng
Ano de publicação:
2016
Tipo de documento:
Article