Cyclosporine in Dermatology.
Skinmed
; 14(2): 105-9, 2016.
Article
em En
| MEDLINE
| ID: mdl-27319953
ABSTRACT
Cyclosporine, a member of the calcineurin inhibitor family, has immunomodulatory effects on T cells. It blocks the earliest stages of the immune response by binding to cyclophilin, thus inhibiting calcineurin. It was initially used for transplant patients to prevent transplant rejections. The main indication for cyclosporine in dermatology is severe psoriasis. Other dermatologic indications for the use of cyclosporine include atopic dermatitis, chronic idiopathic urticaria, pyoderma gangrenosum, and Behçet's disease.
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Base de dados:
MEDLINE
Assunto principal:
Dermatopatias
/
Ciclosporina
/
Fármacos Dermatológicos
/
Imunossupressores
Limite:
Humans
Idioma:
En
Revista:
Skinmed
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2016
Tipo de documento:
Article