Length Matters: MINDY Is a New Deubiquitinase Family that Preferentially Cleaves Long Polyubiquitin Chains.

Maurer, Till; Wertz, Ingrid E

Maurer, Till; Wertz, Ingrid E.

Afiliação

Maurer T; Department of Structural Biology, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
Wertz IE; Departmant of Discovery Oncology, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA; Department of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA. Electronic address: wertz.ingrid@gene.com.

Mol Cell ; 63(1): 4-6, 2016 07 07.

Article em En | MEDLINE | ID: mdl-27392144

RESUMO

Abdul Rehman and colleagues identify a sixth family of deubiquitinase enzymes that are highly conserved throughout eukaryotes and show a remarkable selectivity for cleaving extended Lys-48-linked polyubiquitin chains.

Assuntos

Eucariotos; Poliubiquitina; Enzimas Desubiquitinantes; Humanos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poliubiquitina / Eucariotos Limite: Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google