PKC iota promotes cellular proliferation by accelerated G1/S transition via interaction with CDK7 in esophageal squamous cell carcinoma.

Ni, Sujie; Chen, Lingling; Li, Mei; Zhao, Weijuan; Shan, Xiaohang; Wu, Miaomiao; Cheng, Jialin; Liang, Li; Wang, Yayun; Jiang, Wenyan; Zhang, Jianguo; Ni, Runzhou

Ni, Sujie; Chen, Lingling; Li, Mei; Zhao, Weijuan; Shan, Xiaohang; Wu, Miaomiao; Cheng, Jialin; Liang, Li; Wang, Yayun; Jiang, Wenyan; Zhang, Jianguo; Ni, Runzhou.

Afiliação

Ni S; Department of Medical Oncology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, 226001, China.
Chen L; Department of Gastroenterology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, 226001, China.
Li M; Department of Medical Oncology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, 226001, China.
Zhao W; Department of Gastroenterology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, 226001, China.
Shan X; Department of Gastroenterology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, 226001, China.
Wu M; Department of Gastroenterology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, 226001, China.
Cheng J; Department of Medical Oncology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, 226001, China.
Liang L; Department of Medical Oncology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, 226001, China.
Wang Y; Department of Gastroenterology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, 226001, China.
Jiang W; Department of Medical Oncology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, 226001, China.
Zhang J; Department of Pathology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, 226001, China. zhjg226@sina.com.
Ni R; Department of Gastroenterology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, 226001, China. nrz0513@sina.cn.

Tumour Biol ; 37(10): 13799-13809, 2016 Oct.

Article em En | MEDLINE | ID: mdl-27481515

Assuntos

Biomarcadores Tumorais/metabolismo; Carcinoma de Células Escamosas/secundário; Proliferação de Células; Quinases Ciclina-Dependentes/metabolismo; Neoplasias Esofágicas/patologia; Fase G1; Isoenzimas/metabolismo; Proteína Quinase C/metabolismo; Fase S; Apoptose; Biomarcadores Tumorais/genética; Western Blotting; Carcinoma de Células Escamosas/genética; Carcinoma de Células Escamosas/metabolismo; Quinases Ciclina-Dependentes/genética; Neoplasias Esofágicas/genética; Neoplasias Esofágicas/metabolismo; Feminino; Citometria de Fluxo; Seguimentos; Humanos; Técnicas Imunoenzimáticas; Isoenzimas/genética; Masculino; Pessoa de Meia-Idade; Gradação de Tumores; Invasividade Neoplásica; Metástase Neoplásica; Estadiamento de Neoplasias; Prognóstico; Proteína Quinase C/genética; RNA Mensageiro/genética; Reação em Cadeia da Polimerase em Tempo Real; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Transdução de Sinais; Taxa de Sobrevida; Células Tumorais Cultivadas

Palavras-chave

CDK7; Cell cycle; Esophageal squamous cell carcinoma; PKCÎ¹; Proliferation

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Base de dados: MEDLINE Assunto principal: Proteína Quinase C / Neoplasias Esofágicas / Carcinoma de Células Escamosas / Biomarcadores Tumorais / Fase G1 / Fase S / Quinases Ciclina-Dependentes / Proliferação de Células / Isoenzimas Tipo de estudo: Observational_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Tumour Biol Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

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