3-Bromo-2-Pyrone: An Alternative and Convenient Route to Functionalized Phosphinines.
Chemistry
; 22(36): 12877-83, 2016 Aug 26.
Article
em En
| MEDLINE
| ID: mdl-27482858
ABSTRACT
The facile access to 3-bromo-2-pyrone allows the preparation of 6-bromo-2-trimethylsilyl-phosphinine by a [4+2] cycloaddition with Me3 Si-C≡P for the first time. The regioselectivity of this reaction could be verified by means of single crystal X-ray diffraction of the corresponding W(0) complex. In the presence of ZnBr2 and dppp (1,3-bis(diphenylphosphino)propane) as a bidentate ligand, the bromo-phosphinine quantitatively undergoes a Negishi cross-coupling reaction with PhLi that selectively leads to 6-phenyl-2-trimethylsilyl-phosphinine. This heterocycle could again be characterized by means of X-ray diffraction as a W(0) complex. These results describe a new and convenient route to 2,6-disubstituted phosphinines that makes use of readily available starting materials.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Chemistry
Assunto da revista:
QUIMICA
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Alemanha