Effects of domain composition on catalytic activity of human UDP-glucose:glycoprotein glucosyltransferases.

Takeda, Yoichi; Seko, Akira; Fujikawa, Kohki; Izumi, Masayuki; Kajihara, Yasuhiro; Ito, Yukishige

Takeda, Yoichi; Seko, Akira; Fujikawa, Kohki; Izumi, Masayuki; Kajihara, Yasuhiro; Ito, Yukishige.

Afiliação

Takeda Y; ERATO, Japan Science and Technology Agency (JST), Ito Glycotrilogy Project, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan Department of Biotechnology, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan yukito@riken.jp yotakeda@fc.ritsumei.ac.jp.
Seko A; ERATO, Japan Science and Technology Agency (JST), Ito Glycotrilogy Project, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Fujikawa K; ERATO, Japan Science and Technology Agency (JST), Ito Glycotrilogy Project, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Izumi M; Department of Chemistry, Graduate School of Science, Osaka University, 1-1, Machikaneyama, Toyonaka, Osaka 560-0043, Japan.
Kajihara Y; ERATO, Japan Science and Technology Agency (JST), Ito Glycotrilogy Project, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan Department of Chemistry, Graduate School of Science, Osaka University, 1-1, Machikaneyama, Toyonaka, Osaka 560-0043, Japan.
Ito Y; ERATO, Japan Science and Technology Agency (JST), Ito Glycotrilogy Project, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan Synthetic Cellular Chemistry Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan yukito@riken.jp yotakeda@fc.ritsumei.ac.jp.

Glycobiology ; 26(9): 999-1006, 2016 09.

Article em En | MEDLINE | ID: mdl-27496766

Assuntos

Domínio Catalítico/genética; Glucosiltransferases/química; Glucosiltransferases/genética; Glicoproteínas/química; Sequência de Aminoácidos/genética; Retículo Endoplasmático/enzimologia; Glucose/metabolismo; Glucosiltransferases/metabolismo; Glicoproteínas/metabolismo; Complexo de Golgi/enzimologia; Humanos; Domínios Proteicos; Dobramento de Proteína; Especificidade por Substrato

Palavras-chave

UDP-glucose:glycoprotein glucosyltransferase; calnexin; calreticulin cycle; endoplasmic reticulum glycoprotein quality control; high-mannose-type glycan

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Base de dados: MEDLINE Assunto principal: Glicoproteínas / Domínio Catalítico / Glucosiltransferases Limite: Humans Idioma: En Revista: Glycobiology Assunto da revista: BIOQUIMICA Ano de publicação: 2016 Tipo de documento: Article

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