Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction.

Patzig, Julia; Erwig, Michelle S; Tenzer, Stefan; Kusch, Kathrin; Dibaj, Payam; Möbius, Wiebke; Goebbels, Sandra; Schaeren-Wiemers, Nicole; Nave, Klaus-Armin; Werner, Hauke B

Patzig, Julia; Erwig, Michelle S; Tenzer, Stefan; Kusch, Kathrin; Dibaj, Payam; Möbius, Wiebke; Goebbels, Sandra; Schaeren-Wiemers, Nicole; Nave, Klaus-Armin; Werner, Hauke B.

Afiliação

Patzig J; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Goettingen, Germany.
Erwig MS; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Goettingen, Germany.
Tenzer S; Institute of Immunology, University Medical Center, Johannes Gutenberg University, Mainz, Germany.
Kusch K; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Goettingen, Germany.
Dibaj P; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Goettingen, Germany.
Möbius W; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Goettingen, Germany.
Goebbels S; Center for Nanoscale Microscopy and Molecular Physiology of the Brain, Göttingen, Germany.
Schaeren-Wiemers N; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Goettingen, Germany.
Nave KA; Departement of Biomedicine, University Hospital Basel, Basel, Switzerland.
Werner HB; Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Goettingen, Germany.

Elife ; 52016 08 09.

Article em En | MEDLINE | ID: mdl-27504968

Assuntos

Sistema Nervoso Central/fisiologia; Proteínas Contráteis/metabolismo; Bainha de Mielina/metabolismo; Condução Nervosa; Septinas/metabolismo; Animais; Sistema Nervoso Central/química; Citoesqueleto/metabolismo; Técnicas de Inativação de Genes; Marcação de Genes; Camundongos; Microscopia Confocal; Microscopia Imunoeletrônica; Fibras Nervosas Mielinizadas/química; Fibras Nervosas Mielinizadas/fisiologia; Multimerização Proteica; Proteoma/análise; Proteômica; Septinas/genética

Palavras-chave

glial cells; label-free proteomics; mouse; myelin structure; myelinated axons; neuropathology; neuroscience; septin cytoskeleton

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistema Nervoso Central / Proteínas Contráteis / Septinas / Bainha de Mielina / Condução Nervosa Limite: Animals Idioma: En Revista: Elife Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha

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