Effect of pindolol versus atenolol on lipid profile in hypertensive patients.
Atherosclerosis
; 77(2-3): 215-20, 1989 Jun.
Article
em En
| MEDLINE
| ID: mdl-2751753
ABSTRACT
The effect of pindolol (a beta-blocker with intrinsic sympathomimetic activity, ISA) on fasting plasma lipid profile in 30 hypertensive patients was compared with atenolol (without ISA) in a crossover single blind study. Both drugs lowered blood pressure. HDL-cholesterol increased significantly with pindolol (from 1.15 +/- 0.05 to 1.34 +/- 0.05 mmol/l at 12 weeks, P less than 0.001), but not with atenolol. VLDL-cholesterol increased with atenolol (from 0.57 +/- 0.09 to 0.86 +/- 0.14 mmol/l at 12 weeks, P less than 0.002), while there was no change with pindolol. These changes in lipoprotein profile suggest a more favourable effect of pindolol than of atenolol on lipid profile.
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Base de dados:
MEDLINE
Assunto principal:
Pindolol
/
Atenolol
/
Hipertensão
/
Lipoproteínas
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Atherosclerosis
Ano de publicação:
1989
Tipo de documento:
Article
País de afiliação:
Reino Unido