Tryptophan Residue Located at the Middle of Putative Transmembrane Domain 11 Is Critical for the Function of Organic Anion Transporting Polypeptide 2B1.

Bian, Jialin; Jin, Meng; Yue, Mei; Wang, Meiyu; Zhang, Hongjian; Gui, Chunshan

Bian, Jialin; Jin, Meng; Yue, Mei; Wang, Meiyu; Zhang, Hongjian; Gui, Chunshan.

Afiliação

Bian J; Department of Pharmaceutical Analysis, College of Pharmaceutical Sciences, Soochow University , Suzhou 215123, China.
Jin M; Department of Pharmaceutical Analysis, College of Pharmaceutical Sciences, Soochow University , Suzhou 215123, China.
Yue M; Department of Pharmaceutical Analysis, College of Pharmaceutical Sciences, Soochow University , Suzhou 215123, China.
Wang M; Department of Pharmaceutical Analysis, College of Pharmaceutical Sciences, Soochow University , Suzhou 215123, China.
Zhang H; Department of Pharmaceutical Analysis, College of Pharmaceutical Sciences, Soochow University , Suzhou 215123, China.
Gui C; Department of Pharmaceutical Analysis, College of Pharmaceutical Sciences, Soochow University , Suzhou 215123, China.

Mol Pharm ; 13(10): 3553-3563, 2016 10 03.

Article em En | MEDLINE | ID: mdl-27576593

Assuntos

Transportadores de Ânions Orgânicos/metabolismo; Triptofano/metabolismo; Biotinilação; Cromatografia Líquida; Células HEK293; Humanos; Immunoblotting; Transportadores de Ânions Orgânicos/química; Domínios Proteicos; Estrutura Secundária de Proteína; Espectrometria de Massas em Tandem; Triptofano/química

Palavras-chave

OATP2B1; molecular modeling; transmembrane domain; transporter; tryptophan residue

Buscar no Google

Imprimir

XML

PubMed Links

Base de dados: MEDLINE Assunto principal: Triptofano / Transportadores de Ânions Orgânicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

Buscar no Google

Imprimir

XML

PubMed Links