Treatment of glomus tympanicum tumors by preoperative embolization and total surgical resection.
Am J Otolaryngol
; 37(6): 544-551, 2016.
Article
em En
| MEDLINE
| ID: mdl-27650391
ABSTRACT
PURPOSE:
The purpose of this study was to evaluate the effectiveness on function preservation and tumor control of the treatment of glomus tympanicum tumors with pre-operative embolization followed by total surgical resection. MATERIAL ANDMETHODS:
We describe a series of 6 patients with a glomus tympanicum tumor who were treated in our hospital using the same technique the day before surgery selective tumor embolization due to denaturation with 96% ethanol. Following parameters were considered tumor classification, tumor control, clinical and audiological outcome, effectiveness of embolization, percentage of tumor necrosis and treatment complications.RESULTS:
There were no severe complications due to embolization or surgery. Tumor blush disappeared completely in 5 patients on DSA post embolization and histologic evaluation of the resected tissue showed a median of 69.2% of tumor necrosis. Pulsatile tinnitus disappeared in all patients and 3 patients had no symptoms at all. Hearing ameliorated in 4 patients, 1 patient without hearing loss pre- treatment still had normal hearing after treatment and 1 patient's hearing was worse after treatment. Average follow-up was 21.3months.CONCLUSIONS:
Treatment of glomus tympanicum tumors by pre-operative embolization with ethanol and surgical resection has not been described before. Our results show that it is a safe procedure with a good long term tumor control, good clinical and audiological outcome.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tumor de Glomo Timpânico
/
Embolização Terapêutica
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Aged
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Female
/
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Am J Otolaryngol
Ano de publicação:
2016
Tipo de documento:
Article