Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans.

Atienzar, Franck A; Blomme, Eric A; Chen, Minjun; Hewitt, Philip; Kenna, J Gerry; Labbe, Gilles; Moulin, Frederic; Pognan, Francois; Roth, Adrian B; Suter-Dick, Laura; Ukairo, Okechukwu; Weaver, Richard J; Will, Yvonne; Dambach, Donna M

Atienzar, Franck A; Blomme, Eric A; Chen, Minjun; Hewitt, Philip; Kenna, J Gerry; Labbe, Gilles; Moulin, Frederic; Pognan, Francois; Roth, Adrian B; Suter-Dick, Laura; Ukairo, Okechukwu; Weaver, Richard J; Will, Yvonne; Dambach, Donna M.

Afiliação

Atienzar FA; UCB BioPharma SPRL, Chemin du Foriest, R9 Building, 1420 Braine-l'Alleud, Belgium.
Blomme EA; AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, USA.
Chen M; Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, US Food and Drug Administration (FDA), Jefferson, AR 72079, USA.
Hewitt P; Merck KGaA, Frankfurter Strasse 250, 64293 Darmstadt, Germany.
Kenna JG; Drug Safety Consultant, Macclesfield, Cheshire SK11, UK.
Labbe G; Sanofi, Bâtiment C. Bernard, 13 Quai Jules Guesdes, Zone B, BP14, 94403 Vitry-sur-Seine Cedex, France.
Moulin F; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Silver Spring, MD 20993, USA.
Pognan F; Novartis Pharma AG, Klybeckstrasse 141, 4057 Basel, Switzerland.
Roth AB; Hoffmann La-Roche Inc., 4000 Basel, Switzerland.
Suter-Dick L; School of Life Sciences, University of Applied Sciences Northwestern Switzerland, Gründenstrasse 40, 4132 Muttenz, Switzerland.
Ukairo O; Ipsen Biosciences Inc., 650 E Kendall Street, Cambridge, MA 02142, USA.
Weaver RJ; Institut de Recherches Internationales Servier (IRIS), 50 rue Carnot, 92284 Suresnes Cedex, France.
Will Y; Pfizer R&D, Drug Safety Research and Development, Eastern Point Road, Groton, CT 06340, USA.
Dambach DM; Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.

Biomed Res Int ; 2016: 9737920, 2016.

Article em En | MEDLINE | ID: mdl-27689095

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Biomed Res Int Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Bélgica

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google